Saccharomyces cerevisiae Pathway/Genome Database
YeastCyc is a Pathway/Genome Database of the model eukaryote Saccharomyces cerevisiae S288c. In addition to genomic information, the database contains metabolic pathway, reaction, enzyme, and compound information, which has been manually curated from the scientific literature. The database was generated in 2002 by the SGD project using SRI's Pathway Tools software, and benefited from significant curation by SGD. In 2012 the database was transferred to SRI International, where it is curated by curators from the SRI Bioinformatics Research Group, and from the Boyce Thompson Institute. That curation process includes periodic updates to the metabolites, reactions and pathways from the current version of MetaCyc to ensure compatibility with other members of the MetaCyc family of databases. YeastCyc has been curated from 2,100 publications. For details on recent curation, please click here.
YeastCyc is part of the larger BioCyc collection of thousands of Pathway/Genome Databases for sequenced genomes. Click "change organism database" in the upper right corner to explore the available databases.
User Guide >>
Explore Saccharomyces cerevisiae Metabolic Maps
The Cellular Overview enables you to browse through zoomable metabolic map diagrams that are customized to each BioCyc organism.Learn More
Saccharomyces cerevisiae on your iPhone and iPad
Have you ever wanted to quickly find out what is known about a gene, protein or pathway that was just mentioned in a talk or on a poster? Download the free BioCyc iPhone app to browse BioCyc on the go! Try the iPad version as well.Download Here
RouteSearch: Search for Paths through the Metabolic Network
Search for lowest-cost paths through the metabolic network of the selected organism. Or, design lowest-cost pathways to novel compounds by adding reactions from MetaCyc.Learn More
Build quantitative metabolic flux models using the MetaFlux metabolic modeling component of Pathway Tools.Learn More
Multiple Sequence Alignments
You can now generate multiple sequence alignments for genes or proteins - within a genome or between genomes.Learn More
Metabolomics Data Analysis
Multiple tools are available in this website for metabolomics data analysis.Learn More
Gene Expression Data Analysis
Multiple tools are available in this website for analysis of gene expression data.Learn More
Saccharomyces cerevisiae Comparative Genome Analysis
Multiple comparative analysis tools are available in this website.Learn More
The Components of BioCyc
BioCyc is a database collection. Tier-1 databases such as EcoCyc and HumanCyc are the most highly curated. Most BioCyc databases have been computationally derived from MetaCyc.Learn More
This site includes extensive retrieval, visualization and analysis tools:
- Saccharomyces cerevisiae metabolic map diagram
- Analyze gene expression, metabolomics data
- Store groups of genes and pathways as Smart Tables; browse, analyze, share them
- Saccharomyces cerevisiae genome browser
This website is part of the BioCyc database collection of 18025 microbial genomes.
Retrieve the sequence of your favorite gene:
1. Select your genome of interest by clicking "change organism database" at the top-right of this page.
2. Type the gene name into the "Quick Search" box at the top right of this page.
3. Click on "Gene Search".
4. In the "Operations" menu on the right side, click on the "Nucleotide Sequence" link to retrieve the sequence from the start to the stop codon.
The BioCyc video series introduces users to the basic and advanced features of the BioCyc website and the Pathway Tools software. A complete list of video tutorials is available on the BioCyc webinars page.